Document Detail

A fetal growth standard derived from multiple modalities.
MedLine Citation:
PMID:  11146236     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To create a fetal weight growth standard from published data on ultrasound-dated pregnancies. METHODS: A fetal growth standard was calculated from published birth weight data, sonographic weight standards, and one MRI study. The birth weights from the East Midlands Obstetric Database were modified by an incremental function to compensate for the lower weights of preterm infants. Published sonographic and MRI standards, and the modified birth weight curve were transformed to yield fractional growth curves that express fetal size as a proportion of the expected term weight. These three curves were then averaged, and the standard deviation was taken as 12% of the median. Curves for Europeans and Chinese were then generated. RESULTS: The average curve for fetal weight is a virtually linear function of gestational age, with a weekly weight gain of 5.2% of the expected term birth weight. CONCLUSIONS: Ultrasound-derived fetal growth curves are subject to bias inherent in weight estimation formulae. A standard derived from multiple modalities is likely to be a more robust estimate of normal fetal growth.
M Mongelli; A Biswas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Early human development     Volume:  60     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  171-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, National University Hospital, Lower Kent Ridge Rd., 119074, Singapore, Singapore.
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MeSH Terms
Birth Weight
Embryonic and Fetal Development*
Fetal Weight*
Gestational Age
Magnetic Resonance Imaging
Reference Values
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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