| Is fetal gender associated with adverse perinatal outcome in intrauterine growth restriction (IUGR)? | |
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MedLine Citation:
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PMID: 16157143 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to determine if there is a difference in perinatal outcome by gender among growth-restricted fetuses. STUDY DESIGN: This was a retrospective cohort study of intrauterine growth restriction (IUGR) singleton pregnancies over a 5-year period. Clinical outcomes compared by gender included preterm delivery, perinatal mortality (PNM), respiratory distress syndrome (RDS), grade 3 or 4 intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and periventricular leukomalacia (PVL). Statistical analysis included bivariate and multivariable techniques. RESULTS: Seven hundred and twenty-seven singleton pregnancies with IUGR were identified. Three hundred and forty-six (47.6%) were males. Birth weight was similar between the groups. After adjusting for maternal demographics, medical history, gestational age, mode of delivery, and antenatal corticosteroids, adverse perinatal outcomes were similar between the groups. Severity of outcomes was also similar between males and females (P = .66). CONCLUSION: Male fetuses with IUGR have similar outcomes when compared with female IUGR fetuses. Gender does not play a role in perinatal outcome in the setting of fetal growth restriction. |
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Authors:
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Joanne N Quiñones; David M Stamilio; Kara M Coassolo; George A Macones; Anthony O Odibo |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 193 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-09-13 Completed Date: 2005-10-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1233-7 Citation Subset: AIM; IM |
Affiliation:
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Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Growth Retardation / physiopathology* Humans Logistic Models Male Pregnancy Pregnancy Outcome* Retrospective Studies Sex Factors |
| Grant Support | |
ID/Acronym/Agency:
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K24 HD 01289/HD/NICHD NIH HHS; T32 HD 07110-07/HD/NICHD NIH HHS |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 2006 Nov;195(5):1498; author reply 1498-9
[PMID:
16615921
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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