Document Detail


Is female sex associated with increased survival after out-of-hospital cardiac arrest?
MedLine Citation:
PMID:  15036738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To evaluate survival after out-of-hospital cardiac arrest in relation to sex. METHODS: All patients with out-of-hospital cardiac arrest included in the Swedish Cardiac Arrest Registry between 1990 and 2000 in whom cardiopulmonary resuscitation (CPR) was attempted and who did not have a crew witnessed arrest were included. The registry covers 85% of the inhabitants of Sweden (approximately 8 million inhabitants). P-values were adjusted to differences in age. Survival was defined as patients being hospitalised alive and being alive one month after cardiac arrest. In all, 23,797 patients participated in the survey of which 27.9% were women. RESULTS: Among women 16.4% were hospitalised alive versus 13.2% among men ( P<0.001). After one month 3.0% among women were alive versus 3.4% among men (NS). In a multivariate analysis considering differences in age and various factors at resuscitation female sex was an independent predictor for patients being hospitalised alive (odds ratio 1.66; 95% confidence limits 1.49-1.84) and for being alive after one month (odds ratio 1.27; 95% confidence limits 1.03-1.56). Women differed from men as they were older ( P<0.001 ), had a lower prevalence of witnessed cardiac arrest ( P=0.01), a lower occurrence of bystander CPR (P<0.001), a lower occurrence of ventricular fibrillation as initial arrhythmia (P<0.001) and a lower occurrence of cardiac disease judged to be the cause of cardiac arrest ( P<0.0001 ). On the other hand they had a cardiac arrest at home more frequently ( P<0.001 ). CONCLUSION: Among patients suffering out-of-hospital cardiac arrest in Sweden which was not crew witnessed and in whom resuscitation efforts were attempted, female sex was associated with an increased survival.
Authors:
Johan Herlitz; Johan Engdahl; Leif Svensson; Marie Young; Karl-Axel Angquist; Stig Holmberg
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Resuscitation     Volume:  60     ISSN:  0300-9572     ISO Abbreviation:  Resuscitation     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-03-23     Completed Date:  2004-06-15     Revised Date:  2009-08-25    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  197-203     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Sahlgrenska University Hospital, S-41345 Goteborg, Sweden. johan.herlitz@hjl.gu.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Cardiopulmonary Resuscitation / methods,  mortality*
Child
Child, Preschool
Cohort Studies
Emergency Medical Services
Female
Heart Arrest / mortality*,  therapy*
Humans
Infant
Logistic Models
Male
Middle Aged
Multivariate Analysis
Probability
Registries
Risk Assessment
Sex Factors
Survival Analysis
Sweden

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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