Document Detail


The feasibility of pain treatment at home after adenoidectomy with ketoprofen tablets in small children.
MedLine Citation:
PMID:  11012958     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, we investigated the feasibility of pain treatment using ketoprofen 25 mg tablets (5 mg x kg(-1) x day(-1)) at home in children after daycase adenoidectomy. We also determined the adverse events and the incidence of postoperative bleeding during the first week after surgery. Initially, we studied 611 children aged 1-9 years. The study design was prospective, longitudinal, and open. The final data consisted of 555 (91%) children, and 522 children who received ketoprofen at home. The parents administered four (1-10, median with 10th and 90th percentiles) ketoprofen tablets to their children during the first week. A total of 20% of the parents experienced problems in administering tablets, and problems were three times more common in children under 48 months compared to older children. The main problems were swallowing difficulties and the unpleasant taste of the tablet. Neither serious adverse events, nor clinically significant bleeding occurred. Ketoprofen at the dose of 5 mg x kg(-1) x day(-1) proved to be a safe analgesic in children for short-term use after adenoidectomy.
Authors:
H Kokki; E Nikanne; R Ahonen
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  10     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2000  
Date Detail:
Created Date:  2000-10-19     Completed Date:  2000-10-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  531-5     Citation Subset:  IM    
Affiliation:
Department of Anaesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, Finland.
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MeSH Terms
Descriptor/Qualifier:
Adenoidectomy*
Ambulatory Surgical Procedures
Anti-Inflammatory Agents, Non-Steroidal / adverse effects,  therapeutic use*
Child
Child, Preschool
Female
Humans
Infant
Ketoprofen / adverse effects,  therapeutic use*
Male
Pain, Postoperative / drug therapy*
Prospective Studies
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 22071-15-4/Ketoprofen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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