Document Detail

The feasibility of implementing a dietary sodium reduction intervention among free-living normotensive individuals in south west Nigeria.
MedLine Citation:
PMID:  12019929     Owner:  NLM     Status:  MEDLINE    
High sodium intake is associated with high levels of blood pressure, both among and within populations. However, there have been few intervention studies from Africa reporting blood pressure changes with dietary reduction of sodium. In this study, we tested the feasibility of achieving a reduction in dietary sodium intake in free-living individuals using a dietary intervention among 82 free-living normotensive adults in southwest Nigeria. The participants, 49 men (mean age 47.2 years) and 33 women (mean age 43.6 years), received dietary advice to reduce sodium intake and maintained the reduced sodium diet for a 2-week period. Blood pressure and 24-hour urinary excretion of sodium were measured at baseline and after two weeks on the reduced sodium diet. Baseline 24-hour urinary sodium excretion was 140.5 (SD 53.4) mmol/24 hours among men and 132.6 (SD 48.0) mmol/24 hours among women. Twenty-four hour urinary sodium excretion fell by 76.9 (95% Cl 59.7, 94.1) mmol/24 hours among men, and by 79.4 (95% Cl 59.4, 99.1) mmol/24 hours among women. On the low sodium diet, systolic blood pressure fell by 4.7 (95% CI 1.9, 7.4) mm Hg among men, and by 7.0 (95% CI 2.6, 11.4) mm Hg among women while diastolic blood pressure fell by 1.9 (95% CI -0.3, 4.1) mm Hg among men and by 1.6 (95% CI -1.8, 5.0) mm Hg among women. It is concluded that a significant reduction in sodium intake may be achievable in free-living individuals in this setting using a simple dietary intervention. The findings of this pilot study should encourage more sophisticated intervention studies (such as cross-over trials and double blind randomized clinical trials) in Africans for the elucidation of mechanisms and consequences of hypertension in Blacks.
Adebowale A Adeyemo; T Elaine Prewitt; Amy Luke; O O Omotade; Charles N Rotimi; W R Brieger; Richard S Cooper
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Ethnicity & disease     Volume:  12     ISSN:  1049-510X     ISO Abbreviation:  Ethn Dis     Publication Date:  2002  
Date Detail:
Created Date:  2002-05-21     Completed Date:  2002-11-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9109034     Medline TA:  Ethn Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  207-12     Citation Subset:  IM    
College of Medicine, University of Ibadan, Nigeria.
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MeSH Terms
Blood Pressure
Feasibility Studies
Health Behavior*
Health Education*
Hypertension / prevention & control
Middle Aged
Pilot Projects
Sodium / urine
Sodium, Dietary / administration & dosage*
Grant Support
Reg. No./Substance:
0/Sodium, Dietary; 7440-23-5/Sodium

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