Document Detail


A favorable maternal and neonatal outcome following chemotherapy with etoposide, bleomycin, and cisplatin for management of grade 3 immature teratoma of the ovary.
MedLine Citation:
PMID:  20041106     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Ovarian cancer rarely complicates pregnancy. Usually these malignancies consist of germ cell tumors. Preserving maternal safety along with favorable neonatal outcome is a subject of debate in the management of ovarian cancer during pregnancy. In this report, the authors describe a 25-year-old primigravid woman who was diagnosed to with an ovarian immature teratoma which was diagnosed at 13th weeks of pregnancy during a routine sonography. She underwent oophorectomy at week 21 of her gestation. Then she received three cycles of BEP regimen (bleomycin, etoposide, and cisplatin) during her pregnancy until week 37 of gestation. At 36 weeks she delivered a male baby with mild glandular hypospadia who was otherwise normal. Management of immature teratoma after the first trimester of pregnancy is similar to non-pregnant patients and is safe for both the mother and the fetus.
Authors:
Fatemeh Ghaemmaghami; Fatemeh Abbasi; Akram Ghahghai Nezam Abadi
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Publication Detail:
Type:  Journal Article     Date:  2009-12-28
Journal Detail:
Title:  Journal of gynecologic oncology     Volume:  20     ISSN:  2005-0399     ISO Abbreviation:  J Gynecol Oncol     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-30     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101483150     Medline TA:  J Gynecol Oncol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  257-9     Citation Subset:  -    
Affiliation:
Department of Gynecology Oncology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
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