Document Detail

The fatty meal test: an alternative to stool fat analysis.
MedLine Citation:
PMID:  6637869     Owner:  NLM     Status:  MEDLINE    
In view of the technical difficulties inherent in using stool fat estimations as a parameter of malabsorption, we used a fatty meal absorption test. Children under investigation for failure to thrive were divided into two groups, those having a normal stool fat output (less than 3.2 g/day) constituting the control group, and those having steatorrhea. After a fatty meal containing 25 g of margarine and 25 g of butter fat, we measured the rise of serum triglycerides and chylomicrons hourly for 5 h. Serum triglyceride rise of less than 100 mg/dl or less than 100% above basal values and the appearance of less than 7% of chylomicrons were considered pathological. Of our control group 95% had a normal rise of triglycerides; and 96% of our patients with steatorrhea had an abnormal rise. This test was more reliable than the two-point triglyceride test previously described for the diagnosis of fat malabsorption. The fatty meal test as described here is considered to be a useful test of absorptive function.
R Goldstein; O Blondheim; E Levy; H Stankiewicz; S Freier
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  38     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  763-8     Citation Subset:  AIM; IM    
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MeSH Terms
Celiac Disease / diagnosis*,  metabolism
Child, Preschool
Chylomicrons / blood
Dietary Fats / diagnostic use*
Feces / analysis*
Lipid Metabolism*
Time Factors
Triglycerides / blood
Reg. No./Substance:
0/Chylomicrons; 0/Dietary Fats; 0/Triglycerides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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