Document Detail


A fatality from sevoflurane abuse.
MedLine Citation:
PMID:  17988469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case is presented of a 47-year-old man who died as a result of sevoflurane abuse. Sevoflurane was identified and confirmed by headspace gas chromatography-mass spectrometry. The heart blood sevoflurane concentration was 16 mg/L, and the peripheral blood sevoflurane concentration was 8.0 mg/L. No drugs or other volatile substances were found in the heart blood. The medical examiner ruled that the cause of death was cardiac arrhythmia due to sevoflurane toxicity. Cardiomegaly was listed on Part II of the death certificate. The manner of death was undetermined.
Authors:
Barry Levine; Dawn Cox; Rebecca A Jufer-Phipps; Ling Li; Aaron Jacobs; David Fowler
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  31     ISSN:  0146-4760     ISO Abbreviation:  J Anal Toxicol     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-11-08     Completed Date:  2007-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  534-6     Citation Subset:  IM    
Affiliation:
Office of Chief Medical Examiner, State of Maryland, 111 Penn St., Baltimore, Maryland 21201, USA. blevi001@umaryland.edu
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MeSH Terms
Descriptor/Qualifier:
Anesthetics, Inhalation / analysis,  poisoning*
Arrhythmias, Cardiac / chemically induced
Cause of Death
Fatal Outcome
Forensic Toxicology*
Gas Chromatography-Mass Spectrometry
Humans
Male
Methyl Ethers / analysis,  poisoning*
Middle Aged
Chemical
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Methyl Ethers; 28523-86-6/sevoflurane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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