Document Detail


A fatality from an oral ingestion of methamphetamine.
MedLine Citation:
PMID:  19874669     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case presented is of a 49-year-old white male decedent who admitted to oral ingestion of methamphetamine. He believed he was being followed by the police while walking his daughter to school in the morning and swallowed the "8-ball of meth," which is known to be one-eighth of an ounce or the equivalent of about 3 g. The following autopsy specimens were analyzed for the presence of methamphetamine and amphetamine by gas chromatography-mass spectrometry: femoral blood, urine, bile, vitreous fluid, brain, liver, and gastric contents. Blood drawn at the hospital approximately 12 h after ingestion was also analyzed. The methamphetamine concentration in the hospital blood was 3.0 mg/L, and the concentration in the femoral blood from autopsy was 30 mg/L. Other drugs confirmed included tramadol, lorazepam, and 11-carboxy-Delta(9)-tetrahydrocannabinol. The pathologist ruled the cause of death to be cardiac dysrhythmia due to excited delirium as a result of methamphetamine drug effects. Discussion of the timeline from ingestion to death and the clinical presentation of the decedent are included.
Authors:
Elizabeth Kiely; C Jeff Lee; Laureen Marinetti
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Publication Detail:
Type:  Case Reports; Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  33     ISSN:  1945-2403     ISO Abbreviation:  J Anal Toxicol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-30     Completed Date:  2010-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  557-60     Citation Subset:  IM    
Affiliation:
Montgomery County Coroner's Office, Dayton, Ohio 45402, USA. kielye@mcohio.org
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MeSH Terms
Descriptor/Qualifier:
Amphetamine / analysis,  metabolism
Arrhythmias, Cardiac / chemically induced,  physiopathology
Central Nervous System Stimulants / analysis,  metabolism,  poisoning*
Fatal Outcome
Forensic Toxicology
Gas Chromatography-Mass Spectrometry
Humans
Lorazepam / analysis
Male
Methamphetamine / analysis,  metabolism,  poisoning*
Middle Aged
Tetrahydrocannabinol / analogs & derivatives,  analysis
Tramadol / analysis
Chemical
Reg. No./Substance:
0/Central Nervous System Stimulants; 1972-08-3/Tetrahydrocannabinol; 27203-92-5/Tramadol; 300-62-9/Amphetamine; 537-46-2/Methamphetamine; 64280-14-4/11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; 846-49-1/Lorazepam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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