Document Detail

A fatal chronic ketamine poisoning.
MedLine Citation:
PMID:  15831015     Owner:  NLM     Status:  MEDLINE    
A few papers in the literature reported incident deaths by acute ketamine poisoning. In this paper, we report an unusual homicide caused by chronic ketamine poisoning. The victim was a 34-year old married woman with no previous medical history (except as reported herein) who died in her own home. The court investigation revealed that she was chronically poisoned by her husband over a period of about one year in an act of homicide. Determination of ketamine concentrations in autopsy specimens was carried out with gas-chromatography/mass spectrometry (GC-MS). The results showed that ketamine concentration was 21 microg/mL in gastric contents, 3.8 microg/mL in blood and 1.2 microg/mL in urine. The most striking forensic findings were cardiac muscle fibrosis and hyaline degeneration of small arteries in victim's heart, the pathological features of ketamine poisoning previous reported only in animal studies.
Y Tao; X P Chen; Z H Qin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  50     ISSN:  0022-1198     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-04-15     Completed Date:  2005-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-6     Citation Subset:  IM    
Department of Forensic Medicine, Medical School of Soochow University, Suzhou 215007, PR China.
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MeSH Terms
Anesthetics, Dissociative / poisoning*
Chronic Disease
Ketamine / poisoning*
Myocardium / pathology*
Reg. No./Substance:
0/Anesthetics, Dissociative; 6740-88-1/Ketamine

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