| A fatal case of paraquat ingestion: clinical course and review of pathophysiology. | |
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MedLine Citation:
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PMID: 21119584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Exposure to the dipyridyl herbicide paraquat can cause many manifestations of toxicity, and is a common method of suicide in developing countries. CASE REPORT: We present a case of a 20 year old healthy gentleman who intentionally overdosed on paraquat in a suicide attempt. He presented to the hospital within 4 hours of ingestion. Despite standard supportive measures, the patient's clinical condition worsened. He developed ulceration of his oral mucosa. He also developed acute non-oliguric renal failure and acute liver injury. After his mental status began to deteriorate, the patient expired. CONCLUSIONS: There are several therapies that may have helped this patient's condition. An explanation about the pathophysiology of toxicity and updated information on treatment is provided for this common condition with poor prognosis. |
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Authors:
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Douglas P Olson; Juan A Diaz; Jose Dalio Gomez Jereda |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 16 ISSN: 1643-3750 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-01 Completed Date: 2011-03-16 Revised Date: 2011-06-14 |
Medline Journal Info:
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Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
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Languages: eng Pagination: CS153-6 Citation Subset: IM |
Affiliation:
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Hospital Tela Integrado, Tela, Honduras. Douglas.olson@yale.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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therapeutic use Blood Chemical Analysis Burns, Chemical / drug therapy*, physiopathology Drug-Induced Liver Injury / physiopathology* Fatal Outcome Humans Male Overdose Paraquat / poisoning* Renal Insufficiency / chemically induced, physiopathology* Suicide* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 4685-14-7/Paraquat |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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