| A fatal case of congenital disseminated Langerhans cell histiocytosis. | |
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MedLine Citation:
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PMID: 10503186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a newborn male infant with congenital Langerhans cell histiocytosis (LCH) is presented. At birth, showed cutaneous lesions (papules and vesicles with a haemorrhagic aspect), mucosal and ganglionic involvement. Biopsy of these lesions led to the diagnosis of LCH. At 24 hours of life the patient began with respiratory, hepatic, hematological and renal dysfunction, and died at 72 hours of life, despite corticoid treatment. LHC with vesicles and a rapid and fatal development, has previously only been described in three patients. The differential diagnosis of a disseminated and hemorrhagic vesicular eruption in a newborn infant is extensive and must include LHC. |
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Authors:
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C Goñi-Orayen; R Ruiz-Cano; A Pérez-Martínez; E Escario-Travesedo; M Atienzar-Tobarra; A Martínez-Gutiérrez |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of perinatal medicine Volume: 27 ISSN: 0300-5577 ISO Abbreviation: J Perinat Med Publication Date: 1999 |
Date Detail:
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Created Date: 1999-11-05 Completed Date: 1999-11-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0361031 Medline TA: J Perinat Med Country: GERMANY |
Other Details:
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Languages: eng Pagination: 228-30 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Albacete General Hospital, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Fatal Outcome Histiocytes / pathology Histiocytosis, Langerhans-Cell / congenital*, drug therapy, pathology Humans Infant, Newborn Male Prednisolone / therapeutic use |
| Chemical | |
Reg. No./Substance:
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50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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