Document Detail

Is the fascicle of left bundle branch involved in the reentrant circuit of verapamil-sensitive idiopathic left ventricular tachycardia?
MedLine Citation:
PMID:  14516339     Owner:  NLM     Status:  MEDLINE    
The exact reentrant circuit of the verapamil-sensitive idiopathic left VT with a RBBB configuration remains unclear. Furthermore, if the fascicle of left bundle branch is involved in the reentrant circuit has not been well studied. Forty-nine patients with verapamil-sensitive idiopathic left VT underwent electrophysiological study and RF catheter ablation. Group I included 11 patients (10 men, 1 woman; mean age 25 +/- 8 years) with left anterior fascicular block (4 patients), or left posterior fascicular block (7 patients) during sinus rhythm. Group II included 38 patients (29 men, 9 women; mean age 35 +/- 16 years) without fascicular block during sinus rhythm. Duration of QRS complex during sinus rhythm before RF catheter ablation in group I patients was significant longer than that of group II patients (104 +/- 12 vs 95 +/- 11 ms, respectively, P=0.02). Duration of QRS complex during VT was similar between group I and group II patients (141 +/- 13 vs 140 +/- 14 ms, respectively, P=0.78). Transitional zones of QRS complexes in the precordial leads during VT were similar between group I and group II patients. After ablation, the QRS duration did not prolong in group I or group II patients (104 +/- 11 vs 95 +/- 10 ms, P=0.02); fascicular block did not occur in group II patients. Duration and transitional zone of QRS complex during VT were similar between the two groups, and new fascicular block did not occur after ablation. These findings suggest the fascicle of left bundle branch may be not involved in the antegrade limb of reentry circuit in idiopathic left VT.
Jen-Yuan Kuo; Ching-Tai Tai; Chern-En Chiang; Wen-Chung Yu; Jin-Long Huang; Ming-Hsiung Hsieh; Charles Jia-Yin Hou; Cheng-Ho Tsai; Yu-An Ding; Shih-Ann Chen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  26     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-30     Completed Date:  2004-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1986-92     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Mackay Memorial Hospital, Taipei Medical University, Taipei.
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MeSH Terms
Anti-Arrhythmia Agents / pharmacology*
Bundle of His / surgery*
Bundle-Branch Block / physiopathology*,  surgery
Catheter Ablation
Chi-Square Distribution
Middle Aged
Tachycardia, Ventricular / physiopathology*,  surgery
Verapamil / pharmacology*
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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