| A family study of coeliac disease. | |
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MedLine Citation:
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PMID: 1121023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirteen of 141 cases (9 percent) of overt, biopsy proven coeliac disease had a definitely affected relative. The pattern of inheritance in these families is compatible with an incompletely penetrant autosomal dominant gene. There was a female preponderance in the adults and the sporadic cases, but not in the children or the familial cases. The series included a pair of concordant and probably monozygotic twins. The authors believe that coeliac disease, as defined at present, is a heterogeneous condition. |
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Authors:
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T J David; A B Ajdukiewicz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of medical genetics Volume: 12 ISSN: 0022-2593 ISO Abbreviation: J. Med. Genet. Publication Date: 1975 Mar |
Date Detail:
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Created Date: 1975-06-25 Completed Date: 1975-06-25 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 2985087R Medline TA: J Med Genet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 79-82 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Biopsy Celiac Disease / genetics* Child Diseases in Twins Female Gene Frequency Genes, Dominant Genetic Variation Humans Jejunum / pathology Male Pedigree Phenotype Selection, Genetic Sex Factors |
| Comments/Corrections | |
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