| Is family screening necessary in brucellosis? | |
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MedLine Citation:
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PMID: 19011744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Brucellosis is an endemic disease in Turkey. Simultaneous infections among family members consuming infected dairy products have been reported. The most frequent signs and symptoms are nonspecific, and most human cases remain unrecognized. We aimed to screen family members of index cases with brucellosis. A questionnaire including demographical and epidemiological data was obtained. All cases were tested by slide agglutination tests (Rose Bengal test). Seropositive ones were further tested by tube agglutination tests (Wrigth test). In the index cases, Brucella antibody titers of > or = 1:160 with and without clinical symptoms and 1:80 with clinical symptoms were considered positive and the household members were enrolled into the study. Twenty-eigth index cases were identified among a total of 110 family members. Among family members, 90 (82%) were seronegative whereas 20 were seropositive. Among seropositive cases, 12 were asymptomatic and 8 were symptomatic. The most frequent symptoms of the index cases were fever, headache and arthralgia. Symptomatic cases were treated and asymptomatic ones followed up without therapy for a period of 6-12 months and none developed brucellosis. In conclusion, family members of the patients with brucellosis are under the increased risk of brucellosis because of a common source. Therefore, it can be considered that family screening may lead to early diagnosis of the disease and to the prevention of the complications. |
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Authors:
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F Tabak; E Hakko; B Mete; R Ozaras; A Mert; R Ozturk |
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Publication Detail:
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Type: Journal Article Date: 2008-11-14 |
Journal Detail:
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Title: Infection Volume: 36 ISSN: 0300-8126 ISO Abbreviation: Infection Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-01-23 Completed Date: 2009-03-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365307 Medline TA: Infection Country: Germany |
Other Details:
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Languages: eng Pagination: 575-7 Citation Subset: IM |
Affiliation:
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Cerrahpasa Medical Faculty, Dept. of Infectious Diseases and Clinical Microbiology, University of Istanbul, 34303, Aksaray, Istanbul, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Agglutination Tests Animals Antibodies, Bacterial / blood* Brucella / immunology* Brucellosis / diagnosis*, epidemiology, microbiology, physiopathology Child Child, Preschool Dairy Products Family Characteristics* Female Humans Infant Interviews as Topic Male Mass Screening / methods* Middle Aged Questionnaires Turkey / epidemiology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial |
| Comments/Corrections | |
Comment In:
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Infection. 2008 Dec;36(6):578-9
[PMID:
19020802
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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