Document Detail

The failure modes of biological prosthetic heart valves.
MedLine Citation:
PMID:  11921659     Owner:  NLM     Status:  MEDLINE    
Bioprosthetic heart valves have been used since the 1960s, starting with the use of homograft aortic valves obtained from human cadavers. Today prosthetic heart valves are used widely, and bioprostheses account for close to 40% of all heart-valve replacements. Although most bioprosthesis are still stented porcine aortic valves, the introduction of stentless valves and the increasing use of cryopreserved homograft valves has led to an upsurge of interest in bioprosthesis. There have been significant changes in the handling and fixation of porcine aortic valves; however, their modes of failure remain virtually unchanged, although many bioprosthetic valves now last for considerably longer periods. This article reviews the modes of failure of bioprosthetic heart valves.
J Butany; R Leask
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of long-term effects of medical implants     Volume:  11     ISSN:  1050-6934     ISO Abbreviation:  J Long Term Eff Med Implants     Publication Date:  2001  
Date Detail:
Created Date:  2002-03-29     Completed Date:  2002-09-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9110830     Medline TA:  J Long Term Eff Med Implants     Country:  United States    
Other Details:
Languages:  eng     Pagination:  115-35     Citation Subset:  T    
University Health Network/Toronto General Hospital.
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MeSH Terms
Aortic Valve / pathology*,  surgery*
Heart Valve Diseases / etiology*,  pathology,  surgery
Heart Valve Prosthesis* / adverse effects
Pericardium / surgery
Prosthesis Failure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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