Document Detail


An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome.
MedLine Citation:
PMID:  16226370     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a patient with the varicella zoster viral (VZV) infection of multiple cranial nerves mimicking Garcin syndrome, who initially presented with Ramsay Hunt syndrome (herpes zoster oticus). A 78-year-old man showed left facial palsy with zosteric eruptions in his left auricle and dysphagia, followed by left total ophthalmoplegia. His serum anti-VZV antibody titer was elevated. Cerebrospinal fluid examination revealed pleocytosis with a slightly elevated protein level. He was treated with intravenous acyclovir and corticosteroids. His tongue weakness resolved, and then ocular movement improved. The improvement of facial palsy and swallowing difficulty was delayed. VZV infection should be considered even in patients who show unilateral multiple cranial neuropathy mimicking Garcin syndrome because it is treatable.
Authors:
Kenya Nishioka; Kenji Fujishima; Hirokazu Kobayashi; Yoshikuni Mizuno; Yasuyuki Okuma
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-10-13
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  108     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-02-12     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  772-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Inzunokuni, Shizuoka 410-2295, Japan.
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MeSH Terms
Descriptor/Qualifier:
Acyclovir / administration & dosage
Aged
Cranial Nerve Diseases / diagnosis*,  drug therapy
Deglutition Disorders / diagnosis*,  drug therapy
Drug Therapy, Combination
Facial Paralysis / diagnosis*,  drug therapy
Follow-Up Studies
Herpes Zoster / diagnosis*,  drug therapy
Herpes Zoster Oticus / diagnosis*,  drug therapy
Humans
Hydrocortisone / administration & dosage
Male
Methylprednisolone / administration & dosage
Neurologic Examination / drug effects
Ophthalmoplegia / diagnosis*,  drug therapy
Prednisolone / administration & dosage
Vocal Cord Paralysis / diagnosis*,  drug therapy
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone; 50-24-8/Prednisolone; 59277-89-3/Acyclovir; 83-43-2/Methylprednisolone

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