Document Detail


The extracellular matrix in balloon arterial injury: a novel target for restenosis prevention.
MedLine Citation:
PMID:  9717858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of the extracellular matrix (ECM) in the pathobiology of restenosis has not been fully appreciated. Recent discoveries have shown the ECM to be a complex, heterogeneous structure whose components are dynamically altered in response to vascular injury. This report reviews the structure and function of vascular ECM and the importance of the matrix in modulating the vascular response to arterial injury such as balloon angioplasty and atherosclerosis.
Authors:
W B Batchelor; R Robinson; B H Strauss
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  41     ISSN:  0033-0620     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    1998 Jul-Aug
Date Detail:
Created Date:  1998-09-04     Completed Date:  1998-09-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  35-49     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Balloon / adverse effects*
Animals
Coronary Disease / etiology,  physiopathology,  prevention & control*
Coronary Vessels / injuries*,  physiopathology
Extracellular Matrix / physiology*
Extracellular Matrix Proteins / metabolism
Humans
Recurrence / prevention & control
Chemical
Reg. No./Substance:
0/Extracellular Matrix Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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