Document Detail


An extended multisensory temporal binding window in autism spectrum disorders.
MedLine Citation:
PMID:  20390256     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Autism spectrum disorders (ASD) form a continuum of neurodevelopmental disorders, characterized by deficits in communication and reciprocal social interaction, as well as by repetitive behaviors and restricted interests. Sensory disturbances are also frequently reported in clinical and autobiographical accounts. However, surprisingly few empirical studies have characterized the fundamental features of sensory and multisensory processing in ASD. The current study is structured to test for potential differences in multisensory temporal function in ASD by making use of a temporally dependent, low-level multisensory illusion. In this illusion, the presentation of a single flash of light accompanied by multiple sounds often results in the illusory perception of multiple flashes. By systematically varying the temporal structure of the audiovisual stimuli, a "temporal window" within which these stimuli are likely to be bound into a single perceptual entity can be defined. The results of this study revealed that children with ASD report the flash-beep illusion over an extended range of stimulus onset asynchronies relative to children with typical development, suggesting that children with ASD have altered multisensory temporal function. These findings provide valuable new insights into our understanding of sensory processing in ASD and may hold promise for the development of more sensitive diagnostic measures and improved remediation strategies.
Authors:
Jennifer H Foss-Feig; Leslie D Kwakye; Carissa J Cascio; Courtney P Burnette; Haleh Kadivar; Wendy L Stone; Mark T Wallace
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale     Volume:  203     ISSN:  1432-1106     ISO Abbreviation:  Exp Brain Res     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-21     Completed Date:  2010-08-17     Revised Date:  2010-09-28    
Medline Journal Info:
Nlm Unique ID:  0043312     Medline TA:  Exp Brain Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  381-9     Citation Subset:  IM    
Affiliation:
Department of Psychology and Human Development, Vanderbilt University, Nashville, TN 37232, USA.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Adolescent
Analysis of Variance
Attention / physiology
Auditory Perception / physiology*
Child
Child Development Disorders, Pervasive / physiopathology*
Female
Humans
Illusions / physiology*
Male
Neuropsychological Tests
Photic Stimulation
Reaction Time / physiology
Time Factors
Visual Perception / physiology*
Grant Support
ID/Acronym/Agency:
T32 HD07226/HD/NICHD NIH HHS
Comments/Corrections

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