| An explanation fro chloracne -- an industrial hazard. | |
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MedLine Citation:
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PMID: 50695 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with chloracne were investigated and the results compared with data matched for age and site from patients with acne vulgaris. The ultrastructural appearances of pilo-sebaceous ducts in both groups were similar. The industrial group had significantly fewer C. acnes than the patients with ordinary acne. They also showed a significant increase in the surface lipid percentage composition of squalene, wax ester and cholesterol and this was associated with a significant decrease in the triglyceride free fatty acids and total triglyceride pool. We suggest that the acnegenic agent has produced its effect by modifying the metabolism of the pilo-sebaceous fluid. |
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Authors:
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W J Cunliffe; M Williams; J C Edwards; S Williams; K T Holland; C D Roberts; R L Holmes; D Williamson; W C Palmer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 55 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1975 |
Date Detail:
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Created Date: 1975-11-05 Completed Date: 1975-11-05 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 211-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
/
chemically induced*,
metabolism,
pathology Adult Dermatitis, Occupational / chemically induced Environmental Exposure Humans Hydrocarbons, Chlorinated / poisoning* Lipid Metabolism Male Sebaceous Glands / metabolism Squalene / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Hydrocarbons, Chlorinated; 111-02-4/Squalene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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