Document Detail

An experimental study of mucociliary pathology of the eustachian tube in otitis media with effusion induced by irradiation.
MedLine Citation:
PMID:  2619619     Owner:  NLM     Status:  MEDLINE    
We have examined the function and fine structure of the mucociliary system of the eustachian tube in an experimental study of otitis media with effusion induced by X-ray irradiation. Functional examination demonstrated that the ciliary activity was diminished in such a condition, while morphological observations showed pathological findings including compound cilia, vacuolation of ciliated cells and expansion of intercellular space. These findings show that irradiation-induced otitis media with effusion results in impairment of the mucociliary system. As evidenced by these studies, the mucociliary system in the eustachian tube has an important role in the clearance of fluid produced in the tympanic cavity as well as affording improvement in this disease.
Y Ohashi; Y Nakai; Y Esaki; Y Onoyama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of oto-rhino-laryngology     Volume:  246     ISSN:  0302-9530     ISO Abbreviation:  Arch Otorhinolaryngol     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-15     Completed Date:  1990-03-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0414105     Medline TA:  Arch Otorhinolaryngol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  428-32     Citation Subset:  IM    
Department of Otolaryngology, Osaka City University Medical School, Japan.
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MeSH Terms
Cilia / radiation effects,  ultrastructure
Eustachian Tube / physiopathology*,  radiation effects,  ultrastructure
Guinea Pigs
Microscopy, Electron, Scanning
Otitis Media with Effusion / etiology,  pathology,  physiopathology*
Time Factors

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