Document Detail

The experimental research of rabbit's sclerotomy sites undergoing transconjunctival sutureless vitrectomy.
MedLine Citation:
PMID:  17852188     Owner:  NLM     Status:  MEDLINE    
AIMS: To investigate the healing mechanism of the rabbit's sclerotomy sites undergoing the Transconjunctival Sutureless Vitrectomy (TSV). METHODS: Thirty-two rabbits (Thirty-two eyes) were divided into four groups: The rabbits performed with the core vitrectomy and air tamponade were Group A, performed with the core vitrectomy as Group B, performed with the non-core vitrectomy and air tamponade as Group C, and the non-core vitrectomy as Group D. The sclerotomy sites were observed by the Ultrasound Biomicroscope (UBM model 840, Humphrey Instruments, San Leandro, CA, USA) on days 1, 3, 5, and 9 postoperatively, and the diameter of the internal and the external aperture was estimated on postoperative day 1. The pathological study of the sclerotomy sites on days 3, 5, and 9 postoperatively were investigated under the light microscope. RESULTS: The Ultrasound Biomicroscope and the pathological sections showed that the healing course of the sclerotomy sites lasted nine days. On postoperative day 1, the vitreous incarceration (19/32, 59.4%), the fluid cavity (18/32, 56.3%), and the air cavity under the conjunctiva (7/16, 43.8%) existed in some cases. The diameter of the internal aperture in Group A and Group B was less than Group C and Group D on day 1 postoperatively, P<0.001. The diameter of the external aperture did not show significant difference in any of the groups. The pathological study verified the healing course was the granulation reaction. CONCLUSION: The healing mechanism of the rabbit's sclerotomy sites undergoing the (TSV) is the granulation reaction accompanied with the elastic recovery of the sclera.
Song Zhengyu; Wang Fang; Fan Ying; Qiu Qinghua
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current eye research     Volume:  32     ISSN:  0271-3683     ISO Abbreviation:  Curr. Eye Res.     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-09-13     Completed Date:  2007-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  647-52     Citation Subset:  IM    
Department of Ophthalmology, Shanghai Jiao Tong University Affiliated First People's Hospital, Shanghai, People's Republic of China.
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MeSH Terms
Conjunctiva / surgery
Intraocular Pressure
Microscopy, Acoustic
Sclera / physiology*,  surgery,  ultrasonography
Suture Techniques*
Vitrectomy / methods*
Wound Healing / physiology*

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