Document Detail


An experimental model to perform dynamic studies of exocrine pancreatic secretion in mice.
MedLine Citation:
PMID:  6147952     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An experimental model to perform dynamic studies of exocrine pancreatic secretion from mice has been developed. It consists of a microsurgical procedure in anesthetized mice using a stereoscopic microscope. The bile-pancreatic common duct was individualized, isolated and cannulated. A specially calibrated capillary tube was placed in the free end of the cannula and put on a millimetrical rule. Readings of pure pancreatic juice flow rate were performed minute by minute to obtain a flow rate curve. The procedure allowed the discrimination among increasing betanechol doses of 0.1, 0.2, and 0.4 microgram/g body weight.
Authors:
E L Calvo; M I Vaccaro; A J Maillie; O H Pivetta
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta physiologica et pharmacologica latinoamericana : organo de la Asociación Latinoamericana de Ciencias Fisiológicas y de la Asociación Latinoamericana de Farmacología     Volume:  34     ISSN:  0326-6656     ISO Abbreviation:  Acta Physiol Pharmacol Latinoam     Publication Date:  1984  
Date Detail:
Created Date:  1984-10-17     Completed Date:  1984-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8409686     Medline TA:  Acta Physiol Pharmacol Latinoam     Country:  ARGENTINA    
Other Details:
Languages:  eng     Pagination:  9-13     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bethanechol
Bethanechol Compounds / pharmacology*
Catheterization
Dose-Response Relationship, Drug
Female
Male
Mice
Mice, Inbred DBA
Models, Biological
Pancreatic Juice / secretion*
Chemical
Reg. No./Substance:
0/Bethanechol Compounds; 674-38-4/Bethanechol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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