Document Detail


An experimental-computational analysis of MHV cavitation: effects of leaflet squeezing and rebound.
MedLine Citation:
PMID:  8061869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A combined experimental-computational study was performed to investigate the flow mechanics which could cause cavitation during the squeezing and rebounding phases of valve closure in the 29 mm mitral bileaflet Edwards-Duromedics (ED) mechanical heart valve (MHV). Leaflet closing motion was measured in vitro, and input into a computational fluid mechanics software package, CFD-ACE, to compute flow velocities and pressures in the small gap space between the occluder tip and valve housing. The possibility of cavitation inception was predicted when fluid pressures dropped below the saturated vapor pressure for blood plasma. The computational analysis indicated that cavitation is more likely to be induced during valve rebound rather than the squeezing phase of valve closure in the 29 mm ED-MHV. Also, there is a higher probability of cavitation at lower values of the gap width at the point of impact between the leaflet tip and housing. These predictions of cavitation inception are not likely to be significantly influenced by the water-hammer pressure gradient that develops during valve closure.
Authors:
V B Makhijani; H Q Yang; A K Singhal; N H Hwang
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  3 Suppl 1     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-09-22     Completed Date:  1994-09-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S35-44; discussion S44-8     Citation Subset:  IM    
Affiliation:
CFD Research Corporation, Huntsville, Alabama 35805.
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Blood Pressure
Computer Simulation
Forecasting
Heart Valve Prosthesis*
Humans
Lasers
Materials Testing
Mitral Valve*
Models, Cardiovascular
Pressure
Prosthesis Design
Pulsatile Flow
Rheology
Sensitivity and Specificity
Software
Stress, Mechanical
Surface Properties
Water
Grant Support
ID/Acronym/Agency:
FD01515/FD/FDA HHS
Chemical
Reg. No./Substance:
7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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