| The experimental and clinical use of intravitreal antibiotics to treat bacterial and fungal endophthalmitis. | |
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MedLine Citation:
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PMID: 1081447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The experimental data involving the use of 14 antibacterial and two antifungal agents have been used to establish a rationale for the management of human endophthalmitis. Twelve cases of endophthalmitis treated under our supervision have been described in detail. The eventual visual outcome is related to two factors: (1) time interval between diagnosis and institution of adequate therapy, and (2) the severity of the organism and its ability to produce exotoxins and proteolytic enzymes. Eleven of 12 cases were cured with the recommended dosages of gentamicin and dexamethasone (400 mcg and 360 mcg, respectively). Eight of the 12 patients retained useful vision of 20/200 or better. |
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Authors:
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G A Peyman; D W Vastine; H I Meisels |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Documenta ophthalmologica. Advances in ophthalmology Volume: 39 ISSN: 0012-4486 ISO Abbreviation: Doc Ophthalmol Publication Date: 1975 Nov |
Date Detail:
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Created Date: 1976-03-01 Completed Date: 1976-03-01 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0370667 Medline TA: Doc Ophthalmol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 183-201 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Animals Anti-Bacterial Agents / therapeutic use Antifungal Agents / therapeutic use Bacterial Infections / drug therapy* Candidiasis / drug therapy* Dexamethasone / administration & dosage, therapeutic use Endophthalmitis / drug therapy*, etiology Gentamicins / administration & dosage*, therapeutic use Humans Injections Male Visual Acuity Vitreous Body |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Antifungal Agents; 0/Gentamicins; 50-02-2/Dexamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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