| The experience of a regional pediatric intestinal failure program: Successful outcomes from intestinal rehabilitation. | |
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MedLine Citation:
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PMID: 20466115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aim of this study was to evaluate the clinical experience of a regional multidisciplinary intestinal failure program for children established in 2005. METHODS: Data were collected from a prospective internal database. Univariate analyses were performed to compare pre- and post-treatment outcomes. Median values are reported. RESULTS: Forty-nine children were referred at an age of 7 months. Remnant small bowel length was 29 cm. With follow-up of 14 months, overall patient survival was 88%. Thirteen bowel-lengthening procedures were performed, thereby increasing small bowel length from 83 to 132 cm (P < .05). Enteral autonomy was achieved in 22 patients (45%), and the caloric requirement for parenteral nutrition was decreased from 100% to 41% (P < .01). Conjugated bilirubin was reduced from 4.1 to 0 mg/dL (P < .05). CONCLUSION: A multidisciplinary approach to pediatric intestinal failure that prioritizes intestinal rehabilitation can achieve successful enteral feeding advancement, improved liver function, and excellent survival in intermediate-range follow-up. |
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Authors:
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Patrick J Javid; Frances R Malone; Jorge Reyes; Patrick J Healey; Simon P Horslen |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: American journal of surgery Volume: 199 ISSN: 1879-1883 ISO Abbreviation: Am. J. Surg. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-14 Completed Date: 2010-06-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370473 Medline TA: Am J Surg Country: United States |
Other Details:
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Languages: eng Pagination: 676-9 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA, USA. patrick.javid@seattlechildrens.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Cause of Death* Databases, Factual Enteral Nutrition / methods Female Hospitals, Pediatric Humans Infant Intestine, Small / pathology, surgery*, transplantation Male Parenteral Nutrition / methods Patient Care Team / organization & administration Postoperative Complications / mortality, rehabilitation Probability Program Evaluation Prospective Studies Risk Assessment Severity of Illness Index Short Bowel Syndrome / diagnosis, mortality*, rehabilitation* Survival Analysis Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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