Document Detail

The experience of a regional pediatric intestinal failure program: Successful outcomes from intestinal rehabilitation.
MedLine Citation:
PMID:  20466115     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of this study was to evaluate the clinical experience of a regional multidisciplinary intestinal failure program for children established in 2005. METHODS: Data were collected from a prospective internal database. Univariate analyses were performed to compare pre- and post-treatment outcomes. Median values are reported. RESULTS: Forty-nine children were referred at an age of 7 months. Remnant small bowel length was 29 cm. With follow-up of 14 months, overall patient survival was 88%. Thirteen bowel-lengthening procedures were performed, thereby increasing small bowel length from 83 to 132 cm (P < .05). Enteral autonomy was achieved in 22 patients (45%), and the caloric requirement for parenteral nutrition was decreased from 100% to 41% (P < .01). Conjugated bilirubin was reduced from 4.1 to 0 mg/dL (P < .05). CONCLUSION: A multidisciplinary approach to pediatric intestinal failure that prioritizes intestinal rehabilitation can achieve successful enteral feeding advancement, improved liver function, and excellent survival in intermediate-range follow-up.
Patrick J Javid; Frances R Malone; Jorge Reyes; Patrick J Healey; Simon P Horslen
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  199     ISSN:  1879-1883     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2010-06-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  676-9     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA, USA.
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MeSH Terms
Analysis of Variance
Cause of Death*
Databases, Factual
Enteral Nutrition / methods
Hospitals, Pediatric
Intestine, Small / pathology,  surgery*,  transplantation
Parenteral Nutrition / methods
Patient Care Team / organization & administration
Postoperative Complications / mortality,  rehabilitation
Program Evaluation
Prospective Studies
Risk Assessment
Severity of Illness Index
Short Bowel Syndrome / diagnosis,  mortality*,  rehabilitation*
Survival Analysis
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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