Document Detail


The expanding use of immunosuppression in the treatment of non-infectious ocular disease.
MedLine Citation:
PMID:  1503617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cyclosporin has been used for an increasing number of ocular indications. This review attempts to put into perspective the present scope of cyclosporin use in the treatment of ophthalmic disorders. This includes a review of randomized masked trials performed to date and work done to minimize and characterize cyclosporin induced renal toxicity. In addition, the ocular surface is an ideal target for topical cyclosporin therapy, and the status of this therapeutic approach is reviewed.
Authors:
R Nussenblatt
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of autoimmunity     Volume:  5 Suppl A     ISSN:  0896-8411     ISO Abbreviation:  J. Autoimmun.     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-09-18     Completed Date:  1992-09-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8812164     Medline TA:  J Autoimmun     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  247-57     Citation Subset:  IM    
Affiliation:
Laboratory of Immunology, National Eye Institute, NIH, Bethesda, MD 20892.
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MeSH Terms
Descriptor/Qualifier:
Bromocriptine / therapeutic use
Corneal Transplantation
Cyclosporine / adverse effects,  therapeutic use*
Drug Therapy, Combination
Endophthalmitis / drug therapy
Eye Diseases / drug therapy*
Humans
Immunosuppression
Keratoconjunctivitis / drug therapy
Prednisone / therapeutic use
Uveitis / drug therapy
Chemical
Reg. No./Substance:
25614-03-3/Bromocriptine; 53-03-2/Prednisone; 59865-13-3/Cyclosporine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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