Document Detail

The existence of rhabdoid cells in specified soft tissue sarcomas. Histopathological, ultrastructural and immunohistochemical evidence.
MedLine Citation:
PMID:  2445098     Owner:  NLM     Status:  MEDLINE    
We report the occurrence of rhabdoid cells in several specified soft tissue sarcomas of round cell variety. The rhabdoid cells had an acidophilic cytoplasm containing a globular perinuclear inclusion and were characterised ultrastructurally by the presence of aggregates of 10 nm intermediate filaments. These filaments contained both cytokeratin and vimentin, as demonstrated immunohistochemically. Extensive sampling of soft tissue sarcomas revealed the presence of such cells in different types of soft tissue round cell sarcomas as follows: 12 of 13 cases of epithelioid sarcomas, 8 of 13 synovial sarcomas (composed predominantly of round cells), 6 of 20 extraskeletal myxoid chondrosarcomas and 4 of 4 round celled malignant mesotheliomas. We wish to stress that the appearance of rhabdoid cells is not a monopoly of one particular type of tumour.
M Tsuneyoshi; Y Daimaru; H Hashimoto; M Enjoji
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Virchows Archiv. A, Pathological anatomy and histopathology     Volume:  411     ISSN:  0174-7398     ISO Abbreviation:  Virchows Arch A Pathol Anat Histopathol     Publication Date:  1987  
Date Detail:
Created Date:  1987-12-04     Completed Date:  1987-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8302198     Medline TA:  Virchows Arch A Pathol Anat Histopathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  509-14     Citation Subset:  IM    
Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Cell Aggregation
Inclusion Bodies / ultrastructure*
Keratins / analysis
Sarcoma / analysis,  pathology*,  ultrastructure
Soft Tissue Neoplasms / analysis,  pathology*,  ultrastructure
Vimentin / analysis
Reg. No./Substance:
0/Vimentin; 68238-35-7/Keratins

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