Document Detail


The examination of fatty acid taste with edible strips.
MedLine Citation:
PMID:  22521910     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to determine whether humans could detect long-chain fatty acids when these lipid molecules are delivered to the oral cavity by edible taste strips. For suprathreshold studies, up to 1.7 μmol of stearic acid or linoleic acid was incorporated into 0.03 mm thick, one-inch square taste strips. Normalized taste intensity values for stearic acid were in the barely detectable range, with values equal to, or slightly above control strips. One-third of test subjects described the taste quality as oily/fatty/waxy. Approximately 75% of test subjects could detect the presence of linoleic acid when this fatty acid was incorporated into dissolvable strips. Normalized taste intensity values for linoleic acid were in the weak to moderate range. The most commonly reported taste quality responses for linoleic acid were fatty/oily/waxy, or bitter. When nasal airflow was obstructed, the perceived taste intensity of linoleic acid decreased by approximately 40%. Taste intensity values and taste quality responses for linoleic acid were then compared among tasters and non-tasters of 6-n-propylthiouracil (PROP). Individuals who could detect the bitter taste of PROP reported higher taste intensity values for linoleic acid compared with PROP non-tasters. However, taste quality responses for linoleic acid were similar among both PROP tasters and PROP non-tasters. These results indicate that humans can detect long-chain fatty acids by both olfactory and non-olfactory pathways when these hydrophobic molecules are delivered to the oral cavity by means of edible taste strips. These studies further show that genetic variation in taste sensitivity to PROP affects chemosensory responses to the cis-unsaturated fatty acid (linoleic acid) in the oral cavity.
Authors:
Sahbina Ebba; Ray A Abarintos; Dae G Kim; Melissa Tiyouh; Judith C Stull; Ankur Movalia; Gregory Smutzer
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2012-04-12
Journal Detail:
Title:  Physiology & behavior     Volume:  106     ISSN:  1873-507X     ISO Abbreviation:  Physiol. Behav.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-18     Completed Date:  2012-11-07     Revised Date:  2013-07-18    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  579-86     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Biology, Temple University, Philadelphia, PA 19122, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Analysis of Variance
Dose-Response Relationship, Drug
Fatty Acids / administration & dosage*
Female
Food Preferences / physiology*
Humans
Linoleic Acid / administration & dosage
Male
Middle Aged
Receptors, G-Protein-Coupled / genetics
Taste / genetics,  physiology*
Taste Threshold / genetics,  physiology*
Young Adult
Grant Support
ID/Acronym/Agency:
2R44 DC007291/DC/NIDCD NIH HHS; HHS-N-260-2006-00007-C//PHS HHS; HHSN260-2006 00007-C/JT/NIH HHS; R44 DC007291-03S2/DC/NIDCD NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Receptors, G-Protein-Coupled; 0/taste receptors, type 2; 2197-37-7/Linoleic Acid
Comments/Corrections

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