Document Detail

The evolving approach to paediatric myocarditis: a review of the current literature.
MedLine Citation:
PMID:  21272427     Owner:  NLM     Status:  MEDLINE    
Paediatric myocarditis remains challenging from the perspectives of diagnosis and management. Multiple aetiologies exist and the majority of cases appear to be related to viral illnesses. Enteroviruses are believed to be the most common cause, although cases related to adenovirus may be more frequent than suspected. The clinical presentation is extremely varied, ranging from asymptomatic to sudden unexpected death. A high index of suspicion is crucial. There is emerging evidence to support investigations such as serum N-terminal B-type natriuretic peptide levels, as well as cardiac magnetic resonance imaging as adjuncts to the clinical diagnosis. In the future, these may reduce the necessity for invasive methods, such as endomyocardial biopsy, which remain the gold standard. Management generally includes supportive care, consisting of cardiac failure medical management, with the potential for mechanical support and cardiac transplantation. Treatments aimed at immunosuppression remain controversial. The paediatric literature is extremely limited with no conclusive evidence to support or refute these strategies. This article summarises the current literature regarding aetiology, clinical presentation, diagnosis, and management of myocarditis in paediatric patients.
Lindsay J May; David J Patton; Deborah S Fruitman
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-01-28
Journal Detail:
Title:  Cardiology in the young     Volume:  21     ISSN:  1467-1107     ISO Abbreviation:  Cardiol Young     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-08-26     Completed Date:  2012-03-01     Revised Date:  2012-10-11    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  241-51     Citation Subset:  IM    
Department of Pediatrics, University of Calgary, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, Alberta, Canada.
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MeSH Terms
Biological Markers / blood
Myocarditis* / diagnosis,  etiology,  therapy
Treatment Outcome
Reg. No./Substance:
0/Biological Markers
Comment In:
Cardiol Young. 2012 Aug;22(4):485   [PMID:  22613218 ]

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