Document Detail


The evolution of oocyte donation in China.
MedLine Citation:
PMID:  20423738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To review the experience with and clinical outcomes for recipients of embryos from oocytes donated under different regulatory standards in China. Initially, the oocytes were provided by one of the patient's consanguineous sisters. Then, the oocytes were obtained from another patient treated with assisted reproduction techniques (ART). Presently, oocytes thus produced are cryopreserved for at least 6months before transfer. METHODS: The records from all women treated with ART at First Affiliated Hospital of Zhengzhou University since 2001 were reviewed and the pregnancy rates and clinical outcomes were determined for each of the 3 periods. RESULTS: In the second period, the mean implantation and clinical pregnancy rates were significantly higher for the 22 oocyte recipients than for their donors. In the third period, the rates for the 56 recipients were compared with the 78 other regular ART patients fertilized with their own oocytes. There were 40 live births for 32 of the recipients over 28 cycles, and the rates of implantation and clinical pregnancy were much higher for the recipients than for the other ART patients (P<0.001). CONCLUSION: Using freshly donated eggs yields a higher pregnancy rate but there is a risk of infectious disease. Using frozen oocytes can significantly decrease this risk but implantation rates are lower.
Authors:
Fang Wang; Yingpu Sun; Huijuan Kong; Jing Li; Yingchun Su; Yihong Guo
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Publication Detail:
Type:  Journal Article     Date:  2010-04-25
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  110     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-08-04     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Center for Reproductive Medicine, First Affiliated Hospital of ZhengZhou University, Henan, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
China
Cryopreservation
Embryo Transfer / methods*
Female
Fertilization in Vitro / methods*
Humans
Oocyte Donation / methods*
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Reproductive Techniques, Assisted / statistics & numerical data*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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