Document Detail


The evaluation of left ventricular hypertrophy in hypertensive patients with subclinical hyperthyroidism.
MedLine Citation:
PMID:  16127209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this prospective cross-sectional study was to investigate the hypertrophic effects of endogenous subclinical hyperthyroidism on myocardium and early development of left ventricular hypertrophy (LVH) in essential hypertensive patients accompanied by endogenous subclinical hyperthyroidism. A total of 31 consecutive patients with stage I hypertension were included in the study. Sixteen of them also had endogenous subclinical hyperthyroidism that they were unaware before. The patients and the controls formed out of ten healthy subjects all underwent an investigation of thyroid functions and cardiologic evaluation. The mean wall thickness of the left ventricle in the stage I hypertensive group with endogenous subclinical hyperthyroidism (group I) was significantly increased as compared with both hypertensive patients without thyroid disease (group II) and the control subjects. The mean left ventricle mass was also significantly higher in group I than group II. Both of the patients' groups had an increased prevalence of LVH as compared with the controls. In this study, hypertensive patients with subclinical hyperthyroidism presented more increase in left ventricular mass, suggesting that subclinical hyperthyroidism may contribute to left ventricular hypertrophy forming a natural progression to hypertension. The hypertensive population should always be screened for endogenous subclinical hyperthyroidism, and should be examined for the criteria of left ventricular hypertrophy by echocardiography in early stages.
Authors:
Ismet Tamer; Mehmet Sargin; Haluk Sargin; Mesut Seker; Erhan Babalik; Mustafa Tekce; Ali Yayla
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Endocrine journal     Volume:  52     ISSN:  0918-8959     ISO Abbreviation:  Endocr. J.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-29     Completed Date:  2005-12-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9313485     Medline TA:  Endocr J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  421-5     Citation Subset:  IM    
Affiliation:
Hypertension Unit, Kartal Education and Research Hospital, Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cross-Sectional Studies
Echocardiography
Female
Humans
Hypertension / complications,  epidemiology*
Hyperthyroidism / complications,  epidemiology*,  therapy
Hypertrophy, Left Ventricular / epidemiology*,  etiology,  ultrasonography*
Male
Middle Aged
Prevalence
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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