| The evaluation of interaction between red blood cells in blood coagulation by optical tweezers. | |
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MedLine Citation:
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PMID: 20581665 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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To maintain the life of patients with hemophilia, apoplexy or hemorrhage, appropriate blood coagulation is crucial. To study the microscopic phenomena of blood coagulation and the therapeutic effects of blood medication, optical tweezers were applied to estimate the interaction between red blood cells in the coagulation process. By measuring minimum optical power required to trap the coagulating blood cells, the pN-scale interaction between them can be evaluated. In normal blood sample, the interaction rises in accordance with coagulation time. The addition of heparin attenuates the interaction and postpones the coagulation, whereas the addition of tranexamic acid starts the coagulation early at the beginning and allows the process completed in less time. |
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Authors:
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Bor-Wen Yang; Yu-Hong Mu; Kui-Teng Huang; Zhe Li; Jie-Lung Wu; Yu-An Lin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Volume: 21 ISSN: 1473-5733 ISO Abbreviation: Blood Coagul. Fibrinolysis Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102551 Medline TA: Blood Coagul Fibrinolysis Country: England |
Other Details:
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Languages: eng Pagination: 505-10 Citation Subset: IM |
Affiliation:
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Department of Opto-Electronic System Engineering, R.O.C. bInstitute of Electrical Engineering, Minghsin University of Science and Technology, Hsinchu, Taiwan, R.O.C. bwyang@must.edu.tw |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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