| An evaluation of four CT-MRI co-registration techniques for radiotherapy treatment planning of prone rectal cancer patients. | |
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MedLine Citation:
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PMID: 22190750 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objectives: MRI is the preferred staging modality for rectal carcinoma patients. This work assesses the CT-MRI co-registration accuracy of four commercial rigid-body techniques for external beam radiotherapy treatment planning for patients treated in the prone position without fiducial markers. Methods: 17 patients with biopsy-proven rectal carcinoma were scanned with CT and MRI in the prone position without the use of fiducial markers. A reference co-registration was performed by consensus of a radiologist and two physicists. This was compared with two automated and two manual techniques on two separate treatment planning systems. Accuracy and reproducibility were analysed using a measure of target registration error (TRE) that was based on the average distance of the mis-registration between vertices of the clinically relevant gross tumour volume as delineated on the CT image. Results: An automated technique achieved the greatest accuracy, with a TRE of 2.3 mm. Both automated techniques demonstrated perfect reproducibility and were significantly faster than their manual counterparts. There was a significant difference in TRE between registrations performed on the two planning systems, but there were no significant differences between the manual and automated techniques. Conclusion: For patients with rectal cancer, MRI acquired in the prone treatment position without fiducial markers can be accurately registered with planning CT. An automated registration technique offered a fast and accurate solution with associated uncertainties within acceptable treatment planning limits. |
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Authors:
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C J Dean; J R Sykes; R A Cooper; P Hatfield; B Carey; S Swift; S E Bacon; D Thwaites; D Sebag-Montefiore; A M Morgan |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of radiology Volume: 85 ISSN: 1748-880X ISO Abbreviation: Br J Radiol Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2011-12-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0373125 Medline TA: Br J Radiol Country: England |
Other Details:
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Languages: eng Pagination: 61-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Medical Physics. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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