| Is etretinate dangerous in Papillon-Lefèvre syndrome? | |
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MedLine Citation:
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PMID: 2967778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 23-year-old girl affected by Papillon-Lefèvre syndrome developed, during Etretinate therapy (1 mg/kg/day), two liver abscesses caused by pyogenic bacteria and a subphrenic abscess. The immunological effects of retinoids may precipitate severe infections in patients with Papillon-Lefèvre syndrome, who probably have a basic, even though not always evident, defect of PMN chemotaxis. |
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Authors:
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A Tosti; P Manuzzi; F Bardazzi; A Costa |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Dermatologica Volume: 176 ISSN: 0011-9075 ISO Abbreviation: Dermatologica Publication Date: 1988 |
Date Detail:
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Created Date: 1988-07-18 Completed Date: 1988-07-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0211607 Medline TA: Dermatologica Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 148-50 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University of Bologna, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bacterial Infections / etiology* Chemotaxis, Leukocyte / drug effects Etretinate / adverse effects* Female Humans Keratoderma, Palmoplantar / drug therapy* Liver Abscess / etiology* Neutrophils / drug effects, immunology Papillon-Lefevre Disease / complications, drug therapy*, immunology Subphrenic Abscess / etiology |
| Chemical | |
Reg. No./Substance:
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54350-48-0/Etretinate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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