Document Detail

Is estrogen necessary after hysteroscopic incision of the uterine septum?
MedLine Citation:
PMID:  9050699     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To evaluate the influence of estrogen after hysteroscopic incision of the uterine septum. DESIGN: Prospective, randomized, blinded study. SETTING: A national referral university hospital. PATIENTS: Fifty women in whom hysterosalpingography (HSG) showed a fundal defect and had septate uterus confirmed by laparoscopy. INTERVENTIONS: Preoperative HSG, hysteroscopic incision of the septum, and postoperative HSG. Four patients were omitted from the analysis because the angle of the uterus could not be corrected, as shown by postoperative HSG. Group 1 (23 women) received conjugated estrogen and progesterone postoperatively and group 2 (23 women) received no hormone. MEASUREMENTS AND MAIN RESULTS: The ratios of the length of the septum to the length of the uterus in the HSGs obtained preoperatively (a/b) and postoperatively (a'/b') were calculated and subtracted from each other (a/b - a'/b'). The means of the subtractions in the two groups were compared. The t test was used for statistical comparison. The results showed no statistically significant difference. CONCLUSION: Estrogen has no apparent role after hysteroscopic incision of the septum.
H Dabirashrafi; K Mohammad; N Moghadami-Tabrizi; K Zandinejad; M Moghadami-Tabrizi
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of the American Association of Gynecologic Laparoscopists     Volume:  3     ISSN:  1074-3804     ISO Abbreviation:  J Am Assoc Gynecol Laparosc     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-04-30     Completed Date:  1997-04-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9417443     Medline TA:  J Am Assoc Gynecol Laparosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  623-5     Citation Subset:  IM    
Endoscopy and Fertility Research Center, Mirza Kouchek Khan Hospital, Tehran, Iran.
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MeSH Terms
Double-Blind Method
Estrogen Replacement Therapy*
Middle Aged
Prospective Studies
Uterus / abnormalities*,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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