Document Detail


An estimation of the incidence and demographic picture of the major hemoglobinopathies in Belgium (from a confidential inquiry).
MedLine Citation:
PMID:  18473244     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An estimation of the incidence and demographic picture of the major hemoglobinopathies in Belgium has been approached through a confidential inquiry sent to 228 pediatric and adult hematological departments. Forty-two percent of responses showed that 417 patients are known in Belgium: 83% with sickle cell disease, 13% with beta-thalassemia (beta-thal) major, 2% with beta-thal intermedia, and 1% with Hb H disease. Twenty-five percent of the sickle cell disease patients and 54% of those suffering from a beta-thal major were older than 20 years. Three hospitals ensure the follow-up of 70% of the patients and are situated in Brussels, Belgium; a follow-up of less than 20 patients was reported at 21 centers. These results confirm that sickle cell disease is the major hemoglobinopathy in Belgium; it concerns mostly pediatricians but adult hematologists are also confronted with these pathologies. Therefore, it is necessary to implement integrated programs of prevention and treatment.
Authors:
Béatrice Gulbis; Alice Ferster; Christiane Vermylen; Marie-Françoise Dresse; Anna Vanderfaeillie; André Delannoy; Veerle Labarque; Pierre Philippet; Alain Kentos; Bernard Sztern; Bernard Deprijck; Françoise Vertongen;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hemoglobin     Volume:  32     ISSN:  1532-432X     ISO Abbreviation:  Hemoglobin     Publication Date:  2008  
Date Detail:
Created Date:  2008-05-13     Completed Date:  2008-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705865     Medline TA:  Hemoglobin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  279-85     Citation Subset:  IM    
Affiliation:
Department of Clinical Chemistry, Cliniques Universitaires de Bruxelles, Hopital Erasme, Universite Libre de Bruxelles, Bruxelles, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Belgium / epidemiology
Demography
Female
Follow-Up Studies
Hemoglobinopathies / epidemiology*
Humans
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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