| The establishment of regional identity in the Xenopus blastula. | |
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MedLine Citation:
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PMID: 2776519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The molecules involved in the commitment of Xenopus cells to particular germ layers are unknown. The question has been investigated for the cells of the blastula in in vivo cell transplantation assays and in vitro aggregation assays. Using the former technique, we have shown that vegetal cells become committed before gastrulation, even when placed in inappropriate sites. We could find no evidence of regional determination within the endoderm germ layer at the early gastrula stage. In aggregation assays, animal and vegetal cells sorted incompletely at the mid-blastula stage and more efficiently at the gastrula stage. Their behaviour may be mediated by differential expression of adhesion molecules, which so far remain unidentified. |
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Authors:
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J Heasman; A Snape; A Turner; C C Wylie |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Ciba Foundation symposium Volume: 144 ISSN: 0300-5208 ISO Abbreviation: Ciba Found. Symp. Publication Date: 1989 |
Date Detail:
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Created Date: 1989-10-17 Completed Date: 1989-10-17 Revised Date: 2009-09-29 |
Medline Journal Info:
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Nlm Unique ID: 0356636 Medline TA: Ciba Found Symp Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 99-109; discussion 109-12, 150-5 Citation Subset: IM |
Affiliation:
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Department of Zoology, University of Cambridge, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blastocyst / cytology* Cell Aggregation Endoderm / cytology Gastrula / cytology Morphogenesis Xenopus / embryology* |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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