Document Detail

The establishment of regional identity in the Xenopus blastula.
MedLine Citation:
PMID:  2776519     Owner:  NLM     Status:  MEDLINE    
The molecules involved in the commitment of Xenopus cells to particular germ layers are unknown. The question has been investigated for the cells of the blastula in in vivo cell transplantation assays and in vitro aggregation assays. Using the former technique, we have shown that vegetal cells become committed before gastrulation, even when placed in inappropriate sites. We could find no evidence of regional determination within the endoderm germ layer at the early gastrula stage. In aggregation assays, animal and vegetal cells sorted incompletely at the mid-blastula stage and more efficiently at the gastrula stage. Their behaviour may be mediated by differential expression of adhesion molecules, which so far remain unidentified.
J Heasman; A Snape; A Turner; C C Wylie
Related Documents :
11397009 - Expression of axolotl dazl rna, a marker of germ plasm: widespread maternal rna and ons...
8045529 - Pagetoid spread into the rete testis by testicular tumours.
11956819 - Localization of a specific germ cell marker, dazl1, in testicular germ cell neoplasias.
20948789 - Retrotransposons and germ cells: reproduction, death, and diversity.
19710509 - Migration and proliferation of intact and genetically modified primordial germ cells an...
19856159 - Spermatogenesis and cycle of the seminiferous epithelium.
7459799 - Correlation between numbers of desmosomes and the aggressiveness of transitional cell c...
22927109 - A novel in vitro model of ischaemic preconditioning: its effect on cell viability in hu...
6981839 - Receptors for the third complement component on a proportion of large granular lymphocy...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ciba Foundation symposium     Volume:  144     ISSN:  0300-5208     ISO Abbreviation:  Ciba Found. Symp.     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-17     Completed Date:  1989-10-17     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  0356636     Medline TA:  Ciba Found Symp     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  99-109; discussion 109-12, 150-5     Citation Subset:  IM    
Department of Zoology, University of Cambridge, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blastocyst / cytology*
Cell Aggregation
Endoderm / cytology
Gastrula / cytology
Xenopus / embryology*
Grant Support
//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Factors specifying cell lineages in the leech.
Next Document:  Anticoagulant management of patients with cardiac valve prostheses