| [The establishment of the Marfan syndrome biobank in Hungary]. | |
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MedLine Citation:
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PMID: 22330841 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Collection of data from biological samples, clinical parameters, and lifestyle factors in Hungarian patients with Marfan syndrome. METHODS: In terms of the criteria used for selection, those cases were chosen where the disorder could be clearly diagnosed on the basis of the patients' cardiovascular and systemic symptoms, as well as of their family history, in line with the guidelines set by the Revised Ghent Nosology. RESULTS: For the purposes of developing the biobank used for the research, 102 cases were selected from the Marfan Register (cDNA from 55 patients, genomic DNA and serum from 102 patients). In addition to the samples, data have been obtained by using internationally validated surveys to further examine the role of physical activity, nutrition and various psychological factors. CONCLUSIONS: The establishment of the Marfan Biobank enables scientists to effectively carry out research based on genetic, gene-expression and protein analysis. The biobank also provides new opportunities to study Hungarian patients with Marfan syndrome. |
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Authors:
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Annamária Agota; Bence Agg; Kálmán Benke; József Gábor Joó; Zoltán Langmár; Krisztina Marosi; Zsuzsanna Lelovics; Zsuzsanna Lelelovics; Kitti Deé; Péter Nagy; Bernadett Köles; Endre Horváth; Zsuzsanna Crespo; Zoltán Szabolcs; Zsolt B Nagy |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Orvosi hetilap Volume: 153 ISSN: 0030-6002 ISO Abbreviation: Orv Hetil Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-14 Completed Date: 2012-03-20 Revised Date: 2012-04-30 |
Medline Journal Info:
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Nlm Unique ID: 0376412 Medline TA: Orv Hetil Country: Hungary |
Other Details:
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Languages: hun Pagination: 296-302 Citation Subset: IM |
Affiliation:
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NAGY GÉN Diagnosztikai és Kutatási Kft. Budapest. langmarzoltan@hotmail.com |
Vernacular Title:
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Marfan-szindróma biobankjának létrehozása. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Child DNA Female Humans Hungary Kaplan-Meier Estimate Life Style Male Marfan Syndrome* / diagnosis, genetics, mortality, physiopathology, psychology Middle Aged Motor Activity Mouth Mucosa Nutritional Status Patient Selection Questionnaires RNA Registries* Tissue Banks* |
| Chemical | |
Reg. No./Substance:
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63231-63-0/RNA; 9007-49-2/DNA |
| Comments/Corrections | |
Erratum In:
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Orv Hetil. 2012 Apr 15;153(15):600 Note: Lelelovics, Zsuzsanna [corrected to Lelovics, Zsuzsanna] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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