Document Detail


PET/CT of esophageal cancer: its role in clinical management.
MedLine Citation:
PMID:  18025508     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positron emission tomography (PET)/computed tomography (CT) has important utility and limitations in the initial staging of esophageal cancer, evaluation of response to neoadjuvant therapy, and detection of recurrent malignancy. Esophageal cancer is often treated by using a combined modality approach (chemotherapy, radiation therapy, and esophagectomy); correct integration of PET/CT into the conventional work-up of esophageal cancer requires a multidisciplinary approach that combines the information from PET/CT with results of clinical assessment, diagnostic CT, endoscopic gastroduodenoscopy, and endoscopic ultrasonography. PET/CT has limited utility in T staging of esophageal cancer and relatively limited utility in detection of dissemination to locoregional lymph nodes. However, PET/CT allows detection of metastatic disease that may not be identifiable with other methods. PET/CT is not sufficiently reliable in the individual patient for determination of treatment response in the primary tumor. Interpretation of PET/CT results is optimized by understanding the diagnostic limitations and pitfalls that may be encountered, together with knowledge of the natural history of esophageal cancer and the staging and treatment options available.
Authors:
John F Bruzzi; Reginald F Munden; Mylene T Truong; Edith M Marom; Bradley S Sabloff; Gregory W Gladish; Revathy B Iyer; Tin-Su Pan; Homer A Macapinlac; Jeremy J Erasmus
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  27     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:    2007 Nov-Dec
Date Detail:
Created Date:  2007-11-20     Completed Date:  2008-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1635-52     Citation Subset:  IM    
Copyright Information:
RSNA, 2007
Affiliation:
Division of Diagnostic Imaging, M. D. Anderson Cancer Center, Houston, Tex, USA. bruzzij@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis*,  pathology,  secondary,  therapy
Artifacts
Brain Neoplasms / secondary
Colonic Neoplasms / secondary
Esophageal Neoplasms / diagnosis*,  pathology,  therapy
False Positive Reactions
Humans
Lymphatic Metastasis
Neoplasm Invasiveness
Neoplasm Staging
Positron-Emission Tomography / methods*
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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