Document Detail


The epidural electric stimulation test does not predict local anesthetic spread or consumption in labour epidural analgesia.
MedLine Citation:
PMID:  23341165     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The epidural electrical stimulation test (EEST) is a highly specific and sensitive test for confirming placement of the epidural catheter in the epidural space. The purpose of this study was to investigate if the EEST could predict the spread and consumption of local anesthetic solutions during labour epidural analgesia.
METHODS: This observational study was conducted in labouring parturients requesting epidural analgesia. The EEST was performed after the epidural catheter placement (T0) and repeated five minutes after a test dose with 2% lidocaine 3 mL (T1). The minimum current required to elicit the motor response at each time point was recorded. A loading dose of 0.125% bupivacaine 10 mL and fentanyl 50 μg was administered and followed by patient-controlled epidural analgesia with 0.0625% bupivacaine and fentanyl 2 μg·mL(-1) (baseline infusion 10 mL·hr(-1), bolus dose 5 mL, lockout interval ten minutes, maximum dose 20 mL·hr(-1)). The primary outcome was the correlation between the current required to elicit motor responses at T0 and T1 and the consumption of bupivacaine in the first two hours of epidural administration. The secondary outcomes included the muscle contraction patterns determined by the EEST and the incidence of failed, inadequate, or asymmetric blocks.
RESULTS: The study was conducted in 102 parturients. The mean electric current required to elicit muscle response was 4.43 mA (range 1-10 mA) at T0, 5.97 mA (range 1-14 mA) at T1, and the mean Δ (T1-T0) current was 1.54 mA (range 0-8 mA). There was no correlation between either the mean baseline current required or the Δ (T1-T0) current and the total bupivacaine consumption at two hours. The incidence of inadequate blocks at two hours was 18%; however, none of the catheters required replacement. Unilateral left (34%) or right (31%) leg contraction was the most frequent pattern elicited by the EEST.
CONCLUSIONS: The EEST shows a wide range of electrical current requirements and elicits a variety of muscle twitch patterns on the lower limbs. Although it confirms the epidural placement of the catheter, the EEST cannot be used to predict the spread or consumption of the local anesthetic solution during labour epidural analgesia.
Authors:
Clarita B Margarido; Aleksandra Dlacic; Mrinalini Balki; Louis Furtado; Jose C A Carvalho
Related Documents :
9811165 - Differential efficacy of vasodilators in hypercholesterolaemic rabbits.
15802345 - Relationship between the inoculum dose of streptococcus pneumoniae and pneumonia onset ...
21034485 - Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung in...
3396665 - Pulmonary toxicity of trichloroethylene: induction of changes in surfactant phospholipi...
3212005 - Excitatory and inhibitory cholinergic effects of yohimbine on isolated guinea-pig small...
24355855 - Ammonium removal from wastewater via struvite pyrolysate recycling with mg(oh)2 addition.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-24
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  60     ISSN:  1496-8975     ISO Abbreviation:  Can J Anaesth     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-18     Completed Date:  2013-09-16     Revised Date:  2014-01-13    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  393-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Analgesia, Epidural / methods*
Analgesia, Obstetrical / methods*
Analgesia, Patient-Controlled / methods
Anesthetics, Local / administration & dosage*,  pharmacokinetics
Bupivacaine / administration & dosage*,  pharmacokinetics
Catheterization / methods
Electric Stimulation / methods
Epidural Space
Female
Fentanyl / administration & dosage
Humans
Labor Pain / drug therapy
Muscle Contraction
Pregnancy
Prospective Studies
Sensitivity and Specificity
Time Factors
Chemical
Reg. No./Substance:
0/Anesthetics, Local; UF599785JZ/Fentanyl; Y8335394RO/Bupivacaine
Comments/Corrections
Comment In:
Can J Anaesth. 2013 Dec;60(12):1270-1   [PMID:  24105620 ]
Can J Anaesth. 2013 Dec;60(12):1271

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  25-Hydroxy vitamin D3 modulates dendritic cell phenotype and function in Crohn's disease.
Next Document:  Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agents.