Document Detail

The epidemiology of syphilis in pregnancy.
MedLine Citation:
PMID:  12171669     Owner:  NLM     Status:  MEDLINE    
This study evaluated the magnitude, risk factors and outcomes of syphilis in pregnancy in a large cohort of women in four countries participating in the World Health Organization (WHO) antenatal care trial. All women attending the first prenatal care at each selected clinic were enrolled. Screening at the first antenatal visit was routinely performed with either rapid plasma reagin or Venereal Disease Research Laboratory and confirmed by fluorescent treponemal antibody absorption. All women also had the same syphilis tests after delivery. The initial prevalence, the incidence during pregnancy and the overall prevalence of syphilis at delivery were 0.9%, 0.4% and 1.3% respectively. Risk factors for syphilis during pregnancy were younger age for the incidence and older age and a history of stillbirth for the prevalence. Women with syphilis during pregnancy had significantly more adverse outcomes. We support the recommendation that in addition to the initial testing, a second routine test for syphilis ought to be established early in the third trimester even in low prevalence areas.
P Lumbiganon; G Piaggio; J Villar; A Pinol; L Bakketeig; P Bergsjo; Y Al-Mazrou; H Ba'aqeel; J M Belizán; U Farnot; G Carroli; H Berendes;
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International journal of STD & AIDS     Volume:  13     ISSN:  0956-4624     ISO Abbreviation:  Int J STD AIDS     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-12     Completed Date:  2002-10-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9007917     Medline TA:  Int J STD AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  486-94     Citation Subset:  IM; X    
Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
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MeSH Terms
Cohort Studies
Pregnancy Complications, Infectious / epidemiology*,  prevention & control
Pregnancy Outcome / epidemiology
Prospective Payment Assessment Commission
Prospective Studies
Risk Factors
Syphilis / epidemiology*,  prevention & control

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