Document Detail

The epidemiology of pneumococcal disease in infants and children.
MedLine Citation:
PMID:  7020043     Owner:  NLM     Status:  MEDLINE    
Streptococcus pneumoniae is the most frequent bacterial cause of pneumonia, otitis media, and bacteremia and is the third most common cause of meningitis in infants and children. Infants have the highest rates of pneumococcal disease. Recent studies showed that the peak incidence of meningitis occurs among infants three to five months of age, that of otitis media occurs among infants six to 12 months of age, and that of hospitalization for pneumonia occurs among infants 13 to 18 months of age. A predominance of males was noted in most studies of pneumococcal disease. Blacks have higher rates of bacteremia and meningitis than do whites; this difference is explained only in part by the greater susceptibility to infection of children with sickle cell disease. However, the incidence of otitis media is lower in blacks than in whites. The predominant pneumococcal serotypes change with age, with time, and with geographic location. Certain serotypes are responsible for most cases of bacteremia or meningitis. Types present in the pneumococcal vaccine currently available represent 85% to 97% of the strains that have caused disease in the United States in recent years.
J O Klein
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Reviews of infectious diseases     Volume:  3     ISSN:  0162-0886     ISO Abbreviation:  Rev. Infect. Dis.     Publication Date:    1981 Mar-Apr
Date Detail:
Created Date:  1981-09-25     Completed Date:  1981-09-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7905878     Medline TA:  Rev Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  246-53     Citation Subset:  IM    
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MeSH Terms
Age Factors
Breast Feeding
Carrier State
Continental Population Groups
Otitis Media / microbiology
Pneumococcal Infections / epidemiology*
Pneumonia, Pneumococcal / epidemiology
Sex Factors
Streptococcus pneumoniae / classification
United States
Grant Support
N0 1-A1-5235//PHS HHS

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