Document Detail


The epidemiology of pain in Parkinson's disease.
MedLine Citation:
PMID:  23208197     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Pain occurring in Parkinson's disease (PD) may affect a large proportion of patients. Based on the results of the methodologically more robust case-control studies that detected a significantly greater frequency of pain in PD patients than in control subjects, pain should now be considered as a non-motor symptom of PD. The heterogeneous quality of pain, the variable relationship of pain with parkinsonian motor signs, and the mixed response of pain to dopaminergic drugs suggest complex mechanisms for pain in PD. Some evidence raises the possibility of common mechanisms shared by pain patients, regardless of the clinical heterogeneity of pain and its variable relationship with motor signs.
Authors:
Giovanni Defazio; Angelo Gigante; Paola Mancino; Michele Tinazzi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-4
Journal Detail:
Title:  Journal of neural transmission (Vienna, Austria : 1996)     Volume:  -     ISSN:  1435-1463     ISO Abbreviation:  J Neural Transm     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9702341     Medline TA:  J Neural Transm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Basic Medical Sciences, Neurosciences and Sensory Organs, "Aldo Moro", University of Bari, Policlinico, Piazza Giulio Cesare 1, 70124, Bari, Italy, giovanni.defazio@uniba.it.
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