| An enzyme kinetic model of blood island formation. | |
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MedLine Citation:
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PMID: 18697733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood islands are conglomerations of prevascular stem cells that form during vasculogenesis, a function critical to early vascular and hematopoietic development. In this paper, a model of blood island formation is proposed employing the approach of classical enzyme kinetics. Deterministic simulations of the model show the formation of blood island-like structures. These are compared to murine blood islands. |
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Authors:
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Andrew Matteson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2008-08-11 |
Journal Detail:
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Title: Mathematical medicine and biology : a journal of the IMA Volume: 25 ISSN: 1477-8602 ISO Abbreviation: Math Med Biol Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-01 Completed Date: 2008-11-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101182345 Medline TA: Math Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 233-45 Citation Subset: IM |
Affiliation:
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Department of Mathematics, Mailstop 3368, Texas A & M University, College Station, TX 77843-3368, USA. drew.matteson@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Vessels / cytology, embryology* Embryonic Stem Cells / cytology* Enzymes / metabolism GATA2 Transcription Factor / physiology Hematopoiesis Kinetics Mathematics* Mesoderm / cytology, embryology Mice Models, Biological* Pluripotent Stem Cells / cytology Transforming Growth Factor beta1 / physiology Vascular Endothelial Growth Factor A / physiology |
| Chemical | |
Reg. No./Substance:
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0/Enzymes; 0/GATA2 Transcription Factor; 0/Gata2 protein, mouse; 0/Transforming Growth Factor beta1; 0/Vascular Endothelial Growth Factor A; 0/vascular endothelial growth factor A, mouse |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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