Document Detail


An enzymatic method for calibration of serum lipase assays.
MedLine Citation:
PMID:  3948404     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An enzymatic method for the calibration of a turbidimetric lipase assay is described, based on measurement of free fatty acids liberated by the action of lipase. The substrate of the turbidimetric assay is a colipase-containing triolein emulsion. For determination of the free fatty acids a commercial test kit including acyl-CoA synthetase, acyl-CoA oxidase, and peroxidase is used. Intra- and interassay imprecision (CV) is about 5% at above-normal lipase activities, about 10% at normal values. Temperature coefficients are 1.24 and 1.45, respectively, for measurements at 30 and 37 degrees C vs 25 degrees C.
Authors:
G E Hoffmann; U Neumann; S Hoffmann; P Kaspar; L Weiss
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  32     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-04-03     Completed Date:  1986-04-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  545-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calibration
Fatty Acids, Nonesterified / analysis*
Humans
Lipase / blood*
Nephelometry and Turbidimetry
Swine
Temperature
Chemical
Reg. No./Substance:
0/Fatty Acids, Nonesterified; EC 3.1.1.3/Lipase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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