| The endocrinopathy of POEMS syndrome. | |
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MedLine Citation:
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PMID: 2555917 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe the clinical features and post mortem findings in a patient with POEMS syndrome (P--polyneuropathy, O--organomegaly, E--endocrinopathy, M--M protein, S--skin changes), with particular emphasis on the evolution of the endocrinopathy over a three year period. In addition to gynaecomastia this case exhibited primary hypothyroidism and primary and secondary adrenal and gonadal failure. The widespread nature of the endocrine changes suggests that a circulating substance interferes with the action of trophic hormones, possibly by inhibiting second messenger production. |
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Authors:
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P M Stewart; M A McIntyre; C R Edwards |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Scottish medical journal Volume: 34 ISSN: 0036-9330 ISO Abbreviation: Scott Med J Publication Date: 1989 Oct |
Date Detail:
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Created Date: 1989-12-28 Completed Date: 1989-12-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2983335R Medline TA: Scott Med J Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 520-2 Citation Subset: IM |
Affiliation:
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Department of Medicine, Western General Hospital, Edinburgh. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Endocrine System Diseases
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complications* Gynecomastia / complications Humans Male Middle Aged Paraproteinemias / complications Peripheral Nervous System Diseases / complications* Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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