Document Detail

The endocrine regulation of uterine blood flow in the nonpregnant uterus: a review.
MedLine Citation:
PMID:  7234909     Owner:  NLM     Status:  MEDLINE    
Evidence is presented to demonstrate the role of steroid hormones in the regulation of blood flow through the nonpregnant uterine vasculature. Estrogens appear to increase blood flow, as documented by the observed increases in flow during proestrus and estrus, as well as the response to exogenous hormone stimulation in laboratory animals. The mechanism for the stimulation of blood flow is apparently indirect, and mediated by another vasoactive agent(s) which remains unknown at this time. Conversely, progesterone decreases estrogen-induced uterine blood flow, probably by depleting the amount of available cytoplasmic estrogen receptor.
R Resnik
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  140     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1981 May 
Date Detail:
Created Date:  1981-07-20     Completed Date:  1981-07-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  151-6     Citation Subset:  AIM; IM    
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MeSH Terms
Endocrine Glands / physiology*
Estrogens / pharmacology
Progesterone / pharmacology
Regional Blood Flow / drug effects
Uterus / blood supply,  physiology*
Grant Support
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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