Document Detail

The endocrine polypeptide cells of the human stomach, duodenum, and jejunum.
MedLine Citation:
PMID:  4919258     Owner:  NLM     Status:  MEDLINE    
Thirty specimens of stomach, duodenum, and jejunum, removed at operation, were examined by optical microscopical, cytochemical, and electron microscopical techniques. The overall distribution of four types of endocrine polypeptide cell in the stomach, and three in the intestine, was determined. The seven cell types are described by names and letters belonging to a scheme for nomenclature agreed upon at the 1969 Wiesbaden conference on gastrointestinal hormones. The gastrin-secreting G cell was the only cell for which firm identification with a known hormone was possible. Although there was wide variation in the distribution of the various cells, from one case to another, striking differences were nevertheless observable, with respect to the G cell, between antra from carcinoma and from ulcer cases.
A G Pearse; I Coulling; B Weavers; S Friesen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gut     Volume:  11     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1970 Aug 
Date Detail:
Created Date:  1970-12-03     Completed Date:  1970-12-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  649-58     Citation Subset:  AIM; IM    
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MeSH Terms
Bile Duct Neoplasms / pathology
Carcinoma / pathology
Duodenal Ulcer / pathology
Duodenum / cytology*,  secretion
Fluorescent Antibody Technique
Gastric Mucosa / secretion
Gastrins / secretion
Gastrointestinal Hormones / secretion*
Jejunum / cytology*,  secretion
Microscopy, Electron
Peptides / secretion
Stomach / cytology*,  pathology
Stomach Neoplasms / pathology
Reg. No./Substance:
0/Gastrins; 0/Gastrointestinal Hormones; 0/Peptides

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