| The endocannabinoid system. | |
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MedLine Citation:
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PMID: 17125448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The endocannabinoid system is a complex physiologic system. One of the most important discoveries related to the endocannabinoid system is that cannabinoid-1 receptors are present throughout the body and that they are linked to obesity and cardiometabolic risk. Adipose tissue was historically thought to be an inert, passive storage vehicle. However, recent findings prove that adipose tissue is a complex endocrine organ that releases adipokines, which influence cardiometabolic risk factors. Elevated endocannabinoid system activity is associated with obesity and coupled with excessive food intake and fat accumulation. Strong evidence suggests that the endocannabinoid system affects the surrogate cardiometabolic end points that greatly influence morbidity and mortality. |
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Authors:
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Steven T Boyd |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pharmacotherapy Volume: 26 ISSN: 0277-0008 ISO Abbreviation: Pharmacotherapy Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-27 Completed Date: 2007-03-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8111305 Medline TA: Pharmacotherapy Country: United States |
Other Details:
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Languages: eng Pagination: 218S-221S Citation Subset: IM |
Affiliation:
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Xavier University, Natchitoches, Louisiana 71457, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Endocannabinoids / metabolism* Humans Obesity / metabolism Receptor, Cannabinoid, CB1 / metabolism* Receptor, Cannabinoid, CB2 / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Endocannabinoids; 0/Receptor, Cannabinoid, CB1; 0/Receptor, Cannabinoid, CB2 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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